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This paper presents the development of a remote expert system in urological area to support the prostate cancer diagnosis. The prostate cancer is one of the most common cancers among men and the second most frequent death cause by cancer in men. The combination of expert system with the benefits of remote computing allows that several doctors and client applications of urological area use the benefits of expert system of support the detection of prostate cancer. Once updated the expert system, it is automatically available for use. The rules of the expert system are applied to prostate cancer, and the diseases that puzzle the doctor in the cancer evaluation. The system was tested with real clinical cases for the evaluation of the results of the expert system in comparison with the result the last biopsy of these patients evaluated. The expert system presented good results, showing a great potential to support the physicians in the diagnosis of prostate cancer.