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Acupuncture has been a major part of primary healthcare in China for thousands of years. The acupuncture points or biological active points (BAP), also known as low-resistance spots or good electro-permeable points, have relative lower electric resistance than the surrounding tissues. There are many factors that can affect the measurement of the electric resistance of BAPs. We examined the relationship between the skin electric resistance at the BAPs of the left and the right hand with various contact pressures from 5 subjects. This preliminary study presented here shows there exists a bilateral symmetry of the skin resistance of the corresponding BAPs from the left and the right hands of all chosen subjects over a range of measuring pressure.