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Bio-heat transfer, - heat transfer affecting living organism under the influence of blood perfusion -, is given great and increasing attention in medicine today. One reason is the increasing use of thermal treatment methods in for example heart- and neuro-surgery. Analysis and modelling of the thermal aspects is frequently carried out at every stage of device and method development, as it exhibits unique possibilities to understand the complex interactions present. This work investigates the use of a hybrid bio-heat model/equation, which is subsequently used to analyse temperature measurement during thermal treatment of the prostate.