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Cell-based biosensors for single cell monitoring and drug analysis

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5 Author(s)
Ping Wang ; Dept. of Biomed. Eng., Zhejiang Univ., Hangzhou, China ; Gaixia Xu ; Lifeng Qin ; Ying Xu
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Cell-based biosensors incorporate cells as sensing elements that convert a change in immediate environment to signals conducive for processing. It characterizes with high sensitivity, excellent selectivity and fast response. Cell-based biosensors have been implemented for a number of applications ranging from pharmaceutical screening to environmental pollutant detection. This work demonstrate a novel cell-based biosensor following the principle of light-addressable potentiometric sensor and field effect transistor for detecting the action potential of single living cell under drugs. The experimental results agree with our expectation.

Published in:

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE  (Volume:1 )

Date of Conference:

1-5 Sept. 2004