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Microchip technology in ion-channel research

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2 Author(s)
Sigworth, F.J. ; Dept. of Cellular & Molecular Physiol., Yale Univ., New Haven, CT, USA ; Klemic, K.G.

The electrical activity of living cells can be monitored in various ways, but for the study of ion channels and the drugs that affect them, the patch-clamp techniques are the most sensitive. Recent developments in microfabricated patch-clamp electrodes are reviewed, and technical challenges for the future are discussed.

Published in:

NanoBioscience, IEEE Transactions on  (Volume:4 ,  Issue: 1 )