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Web services are modular web applications that can be independently deployed and invoked by other software or services on the web. This offers enterprises the capability to integrate in-house business services with external Web services to conduct complex business transactions. The integration efficiency and flexibility are critical for services composition. For Web services providing a similar functionality, Quality of Service (QoS) is the main factor to differentiate them. The overall QoS of a business process must meet a user's requirement. In this paper, we propose a broker-based framework to facilitate dynamic integration and adaptation of QoS-aware Web services with end-to-end QoS constraints. The key functions of a dynamic broker include service collection, selection, composition and adaptation. Our study considers both functional and QoS characteristics of Web services to identify the optimal business process solutions.