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Maximum-scoring segment sets

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1 Author(s)
Csuros, M. ; Dept. d''informatique et de recherche operationnelle, Montreal Univ., Que.

We examine the problem of finding maximum-scoring sets of disjoint segments in a sequence of scores. The problem arises in DNA and protein segmentation and in postprocessing of sequence alignments. Our key result states a simple recursive relationship between maximum-scoring segment sets. The statement leads to fast algorithms for finding such segment sets. We apply our methods to the identification of noncoding RNA genes in thermophiles

Published in:

Computational Biology and Bioinformatics, IEEE/ACM Transactions on  (Volume:1 ,  Issue: 4 )