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The need to see compelling evidence before adopting new methods looms greater in large organizations because of their complexity and the need to integrate new technologies and processes with existing ones. To further evaluate agile methods and their underlying software development practices, several Software Experience Center (SEC) member companies initiated a series of activities to discover if agile practices match their organizations' needs. Although each organization evaluated agile methods according to its specific needs, here we attempt to generalize their findings by analyzing some of their common experiences in the particular context of large organizations with well-established structures and processes. We base this analysis on experience collected and shared among four SEC members namely ABB, DaimlerChrysler, Motorola, and Nokia.