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When people make use of the limited, expensive and historical data to build multiple-input and multiple-output nonlinear mathematical model for decision-making, they often face the problems whether or not all of the experimental data can be used directly for modeling, although artificial neural network (ANN) is a good method to describe the non-linear relationship between inputs and outputs. In the paper, decision-making modeling method based on feed forward ANN and data envelopment analysis (DEA) is brought forward. Experimental data were evaluated and projected by DEA, a widely used method to evaluate relative efficiency among decision making units (DMU). Then the experimental data would become more scientific and reasonable, and all of them could be used for decision-making modeling of ANN. Experiments show that the model of ANN, which gained by training these data, is DEA effective. So it is a new method for optimal data utilizing and decision-making modeling. The method is useful to the research, which may only get limited and high cost data after several times or several years of experiments.