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This work investigates the up-link capacity of a multiple-input multiple-output (MlMO) wireless channel subject to finite multipath scattering in the presence of co-channel interference (CCI). We first consider single interferers with fixed position and then extend to cellular systems. We observe that the average capacity of MlMO system in the presence of interference is significantly greater than that of a single-input single-output (SISO) system and a single-output multiple-output (SIMO) system at moderate SNRs. It is presented that the link capacity of a MIMO system could be maximised by means of a spatially-whitened matched filter, which converts the interference uncorrelated between receive antennas. It is shown that the capacity of the finite scatterers channel can be even larger than that of the independent Rayleigh channel through the use of spatial pre-whitening filter.