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Although digital signals have been used as inputs in some DNA computing applications, there has been a small research regarding the application of DNA computing principles in solving DSP problems. This article offers a first step towards filling this gap and thus strengthening the ties between biology and signal processing. By focusing the attention of the article to a specific domain, the author believes that many new exciting applications of DNA computation can be discovered. A short overview of molecular biology and tools commonly used in DNA computing is also provided for presentation purposes. This article offers the signal processing community some future directions regarding the unexplored area of research in biocomputing technology.