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Future communication requires more advanced mobile service and has more users, so the spectrum is becoming one of factors restraining the development. To solve this problem, many new coding, modulating and transmitting techniques are being put forward. The space-time coding technique is just one important method, which has been used in the third generation communication systems. The paper focuses on the anti-interference technique to restrain the interference of co-channel users while simply introducing the concept of space-time block coding. The anti-interference technique uses the relationship among signals to remove the interference, which can enhance the capacity of the communication system by introducing co-channel users. Moreover, the paper submits a strategy to eliminate the effect of co-channel interference by decoding signals by stages while using the different performance of various modulation techniques. The system performance can be enhanced using this strategy, which is very important for enlarging the capacity of the system.