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We present a low-power design for real-time digital image segmentation LSI. We design the CMOS test-chip in a 0.35 μm 2-Poly 3-Metal CMOS technology, based on a boundary active only architecture. The design area for 41 × 31 pixels is 51.1mm2 and the integration density is 26.5pixel/mm2. From the circuit simulations at 3.3V supply voltage and 10MHz clock frequency, we obtain a power dissipation of 21.8mW and an image segmentation time of 23μsec.