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The rectilinear Steiner minimum tree (RSMT) problem is one of the fundamental problems in physical design, especially in routing, which is known to be NP-complete. This paper presents a practical heuristic for RSMT construction based on ant colony optimization (ACO). This algorithm has been implemented on a Sun workstation with Unix operating system and the results have been compared with the GeoSteiner 3.1 and a recent work using batched greedy triple construction (BGTC). Experimental results show that our algorithm, named ACO-Steiner, can get a very short run time and keep the high performance.