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Analysis of signaling pathways in human T-cells using Bayesian network modeling of single cell data

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7 Author(s)
Sachs, K. ; Biol. Eng. Div., MIT, Cambridge, MA, USA ; Perez, O.D. ; Pe'er, D. ; Nolan, C.P.
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We perform network inference ('reverse-engineering') on phospho-specific multi-dimensional flow cytometry measurements of signaling molecules in human T cells using Bayesian networks. Inferred networks are found to have good agreement with known pathways derived from the literature.

Published in:

Computational Systems Bioinformatics Conference, 2004. CSB 2004. Proceedings. 2004 IEEE

Date of Conference:

16-19 Aug. 2004

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