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Inference of S-system models of genetic networks using a genetic local search

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3 Author(s)
Kimura, S. ; RIKEN Genomic Sci. Center, Yokohama, Japan ; Hatakeyama, M. ; Konagaya, A.

In this paper, we propose a new method for the inference of S-system models of large-scale genetic networks. This method employs a technique to decompose the genetic network inference problem into several subproblems, and then applies a genetic local search to each of the subproblems. A local search method utilizing the feature of the S-system model is used as one of the search operators in this genetic local search. Finally, the effectiveness of the proposed method is verified through a genetic network inference problem.

Published in:

Evolutionary Computation, 2003. CEC '03. The 2003 Congress on  (Volume:1 )

Date of Conference:

8-12 Dec. 2003

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