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Performance evaluation of MMP-II:A second-generation small animal PET

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5 Author(s)
Correia, J.A. ; Dept. of Radiol., Massachusetts Gen. Hosp.& Harvard Med. Sch., Boston, MA, USA ; Burnham, C.A. ; Kaufman, D. ; Brownell, A.-L.
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We have completed construction of a second-generation, single-plane small animal PET instrument based on LSO detectors. The second-generation design addresses some of the limitations in the first-generation. The purpose of the work reported here was to characterize the physical performance of this instrument. Results of the performance measurements include: Spatial resolution=1.25 mm at field center and 1.5 mm at 2 cm radius; point source sensitivity=56 cps/uCi,; scatter fractions of 0.019 and 0.056 in 3.8 and 6 cm diameter cylinders respectively; linearity of reconstructed signal within 5% up to 100 uCi/cc and acceptable dead-time performance up to 25 k true cps. Examples of phantom and animal images are also presented.

Published in:

Nuclear Science, IEEE Transactions on  (Volume:51 ,  Issue: 1 )

Date of Publication:

Feb. 2004

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