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We present a sensitivity-based algorithm for total power including dynamic and subthreshold leakage power minimization using simultaneous sizing, Vdd and Vth assignment. The proposed algorithm is implemented and tested on a set of combinational benchmark circuits. A comparison with traditional CVS based algorithms demonstrates the advantage of the algorithm including an average power reduction of 37% at primary input activities of 0.1. We also investigate the impact of various low Vdd values on total power savings.