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With the rise in the availability of scalable network technologies and resources, Service Providers of all kinds (xSPs) are given possibilities to deliver services through Internet in order for all stakeholders to conduct collaborative online e-business. In such context, new trend of e-business features increased interoperability among corporations and individuals in highly dynamic homogeneous and heterogeneous computing environments and therefore, the needs to streamline the e-business activities, decrease costs, increase productivity, and service new revenue opportunities will all demand xSPs to considerably re-define and re-design their applications integration strategy and integration solution. To reach this new paradigm, technologies notably Grid Computing, Semantic Web and the composition of these two, Semantic Grid as building blocks for the alternative integration approach are considered by both business practitioners and academia. This paper discusses that Service Providers are identified to play a key role in functionalizing such approach by adopting new information systems innovation and Internet Application Integration (IAI) is posited as representative of implementation model for building large-scale and ubiquitous e-commerce marketplace.