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It is well known that electromagnetic fields play a critical role in all biological evolutionary processes. The natural low resonant frequency may interact with the biological signaling pathway through liquids, especially in water. Our hypothesis is that the structured water cluster may not only be an excellent carrier for nutrition and energy, but also an excellent carrier for low frequency information. Our preliminary study has shown that low frequency electromagnetic radiation treated clustered water has many attractive biological functions. It is thus important to understand how to modify the structure of water clusters, and store and transfer the low resonant frequency to living cells. This paper presents some related results.