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A mounting base integrated with disk-shaped miniature heat pipe (DMHP) is designed for laser diode TO can package in the present study. The heat spreading performance of the disk-shaped miniature heat pipe is also presented. The present mounting base is made of aluminum (6061 T6) other than the conventional TO can package with oxygen free copper. The mounting base shows different thermal resistance with different working fluid charge volume. By optimizing the working fluid charge volume, the thermal resistance of the present mounting base will become lower than the conventional base with an oxygen free copper disk for TO can package. Moreover, this novel design can be manufactured on a massive scale and the fabrication cost can thus be effectively reduced.