Cart (Loading....) | Create Account
Close category search window

A linear programming based algorithm for multiple sequence alignments

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Hunt, F.Y. ; Math. & Computational Sci. Div., Nat. Inst. of Stand. & Technol., Gaithersburg, MD, USA ; Kearsley, A.J. ; O'Gallagher, A.

In this brief paper we discuss an approach to multiple sequence alignment based on treating the alignment process as a stochastic control problem. The use of a model based on a Markov decision process leads to a linear programming problem whose solution is linked to a suggested alignment. Our goal is to avoid the expense in time and computation encountered when dynamic programming based algorithms are used to align a large number of sequences. The dual linear programming problem can also be defined. We implemented the method on a set of cytochrome p450 sequences and compared our suggested alignments of 3 sequences with that obtained by CLUSTALW.

Published in:

Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE

Date of Conference:

11-14 Aug. 2003

Need Help?

IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.