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Riptide: fast protein identification from mass spectrometer data

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1 Author(s)
Carter, R.J. ; Computational Biosci. Res., Adv. Studies HP Lab., Palo Alto, CA, USA

The biotechfirm target discovery incorporated (TDI) has developed a relatively fast and inexpensive method for protein identification. The final step in their approach involves an algorithm to deduce the terminal amino acid sequence of an unknown intact protein from its fragmentation mass spectrum. TDI's web-published algorithm was taken as a starting point for further research. The algorithm Riptide was developed that matches the output of TDI's algorithm, but demonstrates a 193X speed improvement on a 6-deep sequencing.

Published in:

Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE

Date of Conference:

11-14 Aug. 2003