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In recent years, the joint decoding of combined source and channel coding have shown the capability of delivering performances exceeding that of separately decoded schemes. In this paper, a well-known joint source/channel coding scheme is investigated for possible use in future 4th Generation (4G) direct sequence spread spectrum multiple access (DS/SSMA) code division multiple access (CDMA) communication systems. Due to the availability of potentially large sets of sequences with good correlation characteristics, the DS/SSMA CDMA system considered in this paper employs complex spreading sequences (CSS). A multiuser CSS-based DS/SSMA CDMA communication system was implemented as test platform for the joint source/channel coding scheme. Several families of CSSs, including Zadoff-Chu (ZC), double sideband constant envelope linearly interpolated root-of-unity filtered general chirp-like (DSB CE-LI-RU Filtered GCL), analytical bandlimited complex (ABC) and quadriphase (QPH) sequences are investigated on this platform. Simulated bit error rate (BER) performances are presented for uncoded, separate source and channel coded and joint source/channel coded systems under realistic multipath fading channel conditions.