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Electrode systems for measuring cardiac impedances using optical transmembrane potential sensors and interstitial electrodes-theoretical design

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2 Author(s)
Barr, R.C. ; Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA ; Plonsey, R.

The cardiac electrical substrate is a challenge to direct measurement of its properties. Optical technology together with the capability to fabricate small electrodes at close spacings opens new possibilities. Here, those possibilities are explored from a theoretical viewpoint. It appears that with careful measurements from a well-designed set of electrodes one can obtain structural conductivities, separating intracellular from interstitial values, and longitudinal from transverse. Resting membrane resistance also can be obtained.

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Biomedical Engineering, IEEE Transactions on  (Volume:50 ,  Issue: 8 )