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Clinical practice guidelines (CPG) are used to represent the clinical procedures that must be followed for patient assistance. The utility of these guidelines is counteracted by the costs of making and updating them. Simultaneously, the minimum basic data set (MBDS) is defined as a health-care standard to represent the patients as a reduced number of fourteen data that can be used to share or compare different hospitals or services within the same hospital. Here, an algorithm is proposed that uses the MBDS to automatically generate CPG. The algorithm is tested with the MBDS patient episodes of the Hospital Joan XXIII (Spain) for four pediatric diseases.