Cart (Loading....) | Create Account
Close category search window
 

High Tc SQUID system and magnetic marker for biological immunoassays

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Enpuku, K. ; Dept. of Electron., Kyushu Univ., Fukuoka, Japan ; Kuroda, D. ; Yang, T.Q. ; Yoshinaga, K.

High Tc SQUID system is developed for the detection of the biological binding-reaction between antigen and its antibody. In this measurement, the antibody is labeled with magnetic nanoparticles, and the magnetic signal from the nanoparticles is measured. The excitation field of a few mT is applied in parallel to the SQUID in order to magnetize the nanoparticles. Due to mechanical misalignment, however, the vertical component of the excitation field couples to the SQUID, and degrades the system performance. In order to solve this problem, we develop two methods. One is the use of a compensation field in the case of the flux dam, and the other is the use of a switch instead of the flux dam. We also develop a magnetic marker utilizing Fe3O4 nanoparticle with diameter of d=25 nm. The nanoparticle is embedded in the polymer with typical diameter of 80 nm, and COOH is attached around the surface of the polymer. The properties of the marker are discussed.

Published in:

Applied Superconductivity, IEEE Transactions on  (Volume:13 ,  Issue: 2 )

Date of Publication:

June 2003

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.