By Topic

Method for quantifying volumetric lesion change in interval liver CT examinations

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
C. Meyer ; Dept. of Radiol., Univ. of Michigan Med. Sch., Ann Arbor, MI, USA ; Hyunjin Park ; J. M. Balter ; P. H. Bland

We propose a method of using a relatively low degree of freedom (DOF) warping to accurately measure the interval change of lesions having homogeneous contrast. The setting presented here presupposes the use of interval computed tomography (CT) liver exams. After a 3 × 24 DOF warping of the later examination to match the liver's pose in the earlier exam of the interval pair is performed, the lesion's volume change is estimated using the computed difference volume of the two data sets via a novel method that counts partial volume contributions and is insensitive to slight misregistration. A mathematically generated phantom is used to quantify accuracy in the presence of noise. We also quantify the accuracy of our CT liver registrations using microcoils implanted for chemotherapy. A probabilistic liver atlas is used to support automatic masking and liver-focused registration.

Published in:

IEEE Transactions on Medical Imaging  (Volume:22 ,  Issue: 6 )