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In TDD-CDMA system, the different asymmetrical requirements between uplink (UL) and downlink (DL) in the different base station (BS) and different time, for example, different switch point between UL and DL in TDD-SCDMA system according to asymmetrical traffics, will generate the serious inter-cell interference. From the interference point of view, dynamic channel allocation (DCA) is treated as mandatory on TDD-CDMA systems. In this paper, a novel and advanced DCA algorithm (pathloss assistance-BS noninterference least DCA, PA-BNL DCA) is presented, which is based on radio resource reserving related to pathloss assistance and BS-BS interference resolving mechanisms. Simulation results show the novel DCA can work better than least DCA schemes (least interference for UL and least transmission power for DL) in asymmetrical traffic.