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We look in depth at some of the different capabilities Grids must support. However, because there are several definitions of Grids, we adopt two views of them: those that support e-Science and those that provide an infrastructure with the ability to dynamically link managed resources. These descriptions emphasize a high-level user requirement and the system capability, respectively. We are integrating resources, managing them, and using them to support distributed collaborative engineering and science. Grids must embrace multiple heterogeneous resources and then integrate them. We discuss how this requires the meeting of three worlds: computers, databases, and sensors.