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An open-loop power control algorithm is proposed for best-effort reduction of self-interference in multi-standard Bluetooth radios. By exploiting the automatic repeat request scheme built into Bluetooth data packets, the proposed algorithm estimates whether a running packet error rate is above or below a predefined target and adjusts transmit output power accordingly. The optimum algorithm parameters are chosen through a system simulation that weighs statistical and timing metrics equally. The algorithm dynamics are also simulated in a Rayleigh-fading channel model and shown to converge asymmetrically when increasing or decreasing output power in order to sustain the quality of service for a Bluetooth link.