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We provide a novel sequential estimation and detection approach for multiple-input-multiple-output (MIMO) systems. The basic idea is to design a probabilistic approximation method for the computation of the maximum a posterior distribution (MAP) via the sequential Monte Carlo methods (SMC). The SMC method has two advantages over the other methods in that it is a blind method and can be computed in parallel. Furthermore, the SMC has characteristics of soft-input and soft-output in nature and, thus, it can be employed as the first stage demodulator in a turbo receiver for a coded MIMO system. Such a turbo receiver successively improves the receiver performance by iteratively exchanging the so-called extrinsic information with the MAP outer channel decoder. Finally, the performance of the proposed sequential Monte Carlo receiver is demonstrated through computer simulations for MIMO systems over single-path and multipath fading channels.