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The combination of space-time block coding (STBC) and direct-sequence code-division multiple access (DS-CDMA) has the potential to increase the performance of multiple users in a cellular network. However, if not carefully designed, the resulting transmission scheme suffers from increased multiuser interference (MUI), which dramatically deteriorates the performance. To tackle this MUI problem in the downlink, we combine two specific DS-CDMA and STBC techniques, namely single-carrier block transmission (SCBT) DS-CDMA and time-reversal STBC. The resulting transmission scheme allows for deterministic maximum-likelihood (ML) user separation through low-complexity code-matched filtering, as well as deterministic ML transmit stream separation through linear processing. Moreover, it can achieve maximum diversity gains of NTNR(L+1) for every user in the system, irrespective of the system load, where NT is the number of transmit antennas, NR the number of receive antennas, and L the order of the underlying multipath channels. In addition, it turns out that a low-complexity linear receiver based on frequency-domain equalization comes close to extracting the full diversity in reduced, as well as full load settings. In this perspective, we also develop two (recursive) least squares methods for direct equalizer design. Simulation results demonstrate the outstanding performance of the proposed transceiver compared to competing alternatives.