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On the use of hybrid multivariable models for predicting human response to anesthesia

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4 Author(s)
Hui Hung Lin ; Illinois Univ., Urbana, IL, USA ; Beck, C. ; Bloom, M. ; Chudoung, J.

The standard modeling paradigm used to describe the relationship between input anesthetic agents and output patient endpoint variables are single-input single-output pharmacokinetic-pharmacodynamic compartment models. We investigate the use of hybrid multivariable models to describe the relations between inputs that include anesthesia, surgical stimuli and disturbances to a variety of patient output variables. Data-based modeling methods are employed. Simulated and measured responses are compared.

Published in:

Decision and Control, 2002, Proceedings of the 41st IEEE Conference on  (Volume:1 )

Date of Conference:

10-13 Dec. 2002

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