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We investigate the chip-level equalization using finite impulse response (FIR) equalizers for the mobile station of code division multiple access (CDMA) systems with single and multiple receive antennas. As a semi-blind method, a generalized minimum mean square error (MMSE) equalization, which combines the MMSE and blind approaches together, is investigated. It is shown that the generalized MMSE equalizer can effectively increase the number of samples to track the variation of channel and thereby performs better when the coherence time is small. In addition, we derive a closed-form solution of the MMSE and generalized MMSE equalizers for given channels.