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Rib waveguides have been fabricated in pulsed-laser-deposited Ti:sapphire layers using photolithographic patterning and subsequent Ar+-beam milling. Fluorescence output powers up to 300 μW have been observed from the ribs following excitation by a 3-W multiline argon laser. Mode intensity profiles show high optical confinement and the measured beam propagation factors Mx2 and My2 of 1.12 and 1.16, respectively, indicate single transverse-mode fluorescence emission. Loss measurements using the self-pumped phase conjugation technique have yielded comparable values (1.7 dB/cm) for the ribs and the unstructured planar waveguide counterparts. The combination of optimum modal properties and strong optical confinement, together with sufficient levels of fluorescence output, make the single-moded Ti:sapphire rib waveguides a very interesting candidate as a fluorescence source for optical coherence tomography applications.