By Topic

The simulation study of the influence of electrical asynchrony on regional mechanics of the ischemic ventricle using electromechanical heart models

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Xia, L. ; Dept. of Biomed. Eng., Zhejiang Univ., Hangzhou, China ; Huo, M. ; Liu, F.

Using mathematical modeling method, this paper investigates the interactions between electrical conduction and mechanical function in the ischemia or infarcted ventricle. The influence of electrical asynchrony on regional mechanics of the ventricle is simulated based on electromechanical heart models. Regional deformation, strain and stress are calculated during systole phase. The preliminary results show that considerable disruption of the contraction pattern occurs in the near ischemic zone, the minimum principal strains in local infarction regions were significantly smaller than those in corresponding regions of the normal heart, while the stresses are larger than those of normal tissues. The simulated results are compared with dog experiments and solutions obtained in the literature. This simulation suggests that such coupled heart models can be used to assess the mechanical function of the ventricle with diseases such as myocardial ischemic or infarction.

Published in:

Computers in Cardiology, 2002

Date of Conference:

22-25 Sept. 2002