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Nonlinear model for offline correction of pulmonary waveform generators

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5 Author(s)
Reynolds, J.S. ; Health Effects Lab. Div., Nat. Inst. for Occupational Safety & Health, Morgantown, WV, USA ; Stemple, K.J. ; Petsko, R.A. ; Ebeling, T.R.
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Pulmonary waveform generators consisting of motor-driven piston pumps are frequently used to test respiratory-function equipment such as spirometers and peak expiratory flow (PEF) meters. Gas compression within these generators can produce significant distortion of the output flow-time profile. A nonlinear model of the generator was developed along with a method to compensate for gas compression when testing pulmonary function equipment. The model and correction procedure were tested on an Assess Full Range PEF meter and a Micro DiaryCard PEF meter. The tests were performed using the 26 American Thoracic Society standard flow-time waveforms as the target flow profiles. Without correction, the pump loaded with the higher resistance Assess meter resulted in ten waveforms having a mean square error (MSE) higher than 0.001 L2/s2. Correction of the pump for these ten waveforms resulted in a mean decrease in MSE of 87.0%. When loaded with the Micro DiaryCard meter, the uncorrected pump outputs included six waveforms with MSE higher than 0.001 L2/s2. Pump corrections for these six waveforms resulted in a mean decrease in MSE of 58.4%.

Published in:

Biomedical Engineering, IEEE Transactions on  (Volume:49 ,  Issue: 12 )