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Force history dependence of reverse-rates of P-selectin interacting with PSGL-1

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3 Author(s)
Zhu, C. ; Sch. of Mech. Eng., Georgia Inst. of Technol., Atlanta, GA, USA ; Marshall, B.T. ; McEver, R.P.

The rates of dissociation of P-selectin bonded with two forms of PSGL-1 and an antibody were characterized using an atomic force microscope. The reverse-rates were shown to depend not only on force but also on the history of force application.

Published in:

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:1 )

Date of Conference:

2002

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