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The design of a 915-MHz diathermy dielectric-loaded applicator with a TE10-mode aperture field distribution is described. The lightweight porous dielectric used for loading the applicator allows for the transmission of refrigerated air through the cavity to provide surface cooling so therapeutic temperature can be produced in deep tissues without excessive heating of surface tissues. The design is based on theoretical calculations previously developed by the authors which predict optimal size of the aperture and field distribution that would provide the best heating patterns in deep layers of tissue. Experimental evaluations of the heating of tissues of models and human beings are discussed.