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Extracting kinetic information from dynamic imaging protocols: a Bayesian approach to parametric image analysis

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4 Author(s)
Spilker, M.E. ; Dept. of Bioeng., Univ. of Washington, Seattle, WA, USA ; Vicini, P. ; Ka-Loh Lie ; Brasch, R.C.

A Bayesian method is proposed to determine regularized parametric images from dynamic imaging protocols. The approach allows to estimate functional parameters from a mathematical model of contrast agent kinetics, and to regularize such estimate using Bayesian approaches. Simulation studies and preliminary analysis of real contrast-enhanced MRI data from mammary tumors in an animal model are encouraging.

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Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:2 )

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