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This paper describes methods for the reduction of jitter in transmission chains with regenerative repeaters. These methods are based on the application of pattern transformations to the output signals of successive repeaters. As a result, the coherent accumulation of jitter from signal dependent jitter sources is prevented. Instead, the jitter accumulates on a power basis. It is shown that in this way a significant reduction of jitter is obtained. This result is demonstrated by both theoretical data and measurements on an experimental transmission chain which correspond fairly closely. Furthermore, the realization of the pattern transformations by simple coding techniques is presented in detail.