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Variability of tissue optical properties in cancer patients receiving photodynamic therapy

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6 Author(s)
Jacques, S.L. ; Providence St. Vincent Med. Center, OR, USA ; Bargo, P. ; Goodell, T. ; Sleven, R.
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Photodynamic Therapy (PDT) uses light to activate photosensitive drug to yield oxidative injury to targeted tissues such as cancer. The ability of treatment light to penetrate a tissue and activate the drug that has accumulated in a target tissue depends on the tissue optical properties, especially the blood perfusion. An endoscopic spectroscopic probe was developed for monitoring esophageal and lung tissues and tested in patients in a pilot clinical study.

Published in:

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:3 )

Date of Conference:

23-26 Oct. 2002