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First chronic results from a flexible sieve electrode to interface nerves without the need for guidance channels

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6 Author(s)
Stieglitz, T. ; Fraunhofer Inst. for Biomed. Eng., St. Ingbert, Germany ; Rosahl, S.K. ; Poessnecker, J. ; Haastert, K.
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Nerves has been previously interfaced with micromachined sieve electrodes for recording and stimulation purposes. In most cases, so-called guidance channels have to be assembled on the sieve to adjust and fix the nerve in the vicinity of the microstructure. In this paper, a new approach of a flexible, polyimide-based sieve electrode is presented. Monolithically integrated fixation flaps offer the opportunity to directly fix the sieve implant on a transected nerve without the need for a guidance channel. The sieve has been fabricated with a thickness of 10 μm and chronically implanted between the transected ends of the sciatic nerve of rats. First electrophysiological experiments proved a functional reinnervation and a selective and graded stimulation over ring electrodes around single holes of 40 μm diameter in the sieve area.

Published in:

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:3 )

Date of Conference:

23-26 Oct. 2002