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Extracting fractal features for analyzing protein structure

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3 Author(s)
Yu Tao ; Shenzhen Graduate Sch., Tsinghua Univ., Beijing, China ; Ioerger, T.R. ; Sacchettini, J.C.

This paper is concerned with the development of a computational methodology based on fractal geometry for determining 3D structure of protein with imagery projection operations. In this investigation, the density-map image is a 2D projection of the 3D electron density map according to its depth of the density distribution along the projection direction. We extract fractal features of the density-map image in a region and use these features to look for candidate regions with similar patterns of density-map. We analyze its fractal signatures for determining 3D pattern of regions of density distribution. This paper presents preliminary results of such a study, wherein the protein surface was assumed to be a fractal, and computed fractal features (fractal dimension and fractal signature) were analyzed and found to possess fairly reasonable pattern for improving the discrimination abilities of the protein structure.

Published in:

Pattern Recognition, 2002. Proceedings. 16th International Conference on  (Volume:2 )

Date of Conference:

2002