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This paper introduces an automated circuit design system for the evolution and subsequent invention of CMOS amplifiers. The proposed system relies on a mix of genetic programming and a new topology-independent design optimization method referred to as current-flow analysis. Genetic programming evolves new circuit topologies from the collection of primitive devices and basic building blocks. Current-flow analysis screens and corrects circuits using topology-independent design rules. Experimental results show a promising improvement on the design of operational amplifiers that make the automated analog design environment using genetic programming a lot more practical.