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Local hyperthermia based on soft heating method utilizing temperature-sensitive ferrite rod

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6 Author(s)
Matsuki, H. ; Dept. of Electr. Eng., Tohoku Univ., Sendai, Japan ; Satoh, T. ; Murakami, K. ; Hoshino, T.
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A description is given of soft heating, an induction heating method which uses an implantable heater consisting of temperature-sensitive magnetic materials and a metal ring. Local hyperthermia based on soft heating is experimentally shown to be effective. A phantom test reveals that a piece of heater supplies sufficient heat to surrounding tissues whose volume is 1 cm3. Wister rats and Walker Carcinosarcoma 256 were used in an animal experiment. Tumors in five rats vanished almost completely after four heating treatments. The accuracy of the regulation is ±0.2°C near the Curie temperature, which can be readily varied

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Magnetics, IEEE Transactions on  (Volume:26 ,  Issue: 5 )