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A pixel chip is presented, employing an asynchronous architecture capable of simultaneous imaging and spectroscopy, on a real-time basis, with no external control signals. The mixed analog-digital architecture has been implemented using a commercial 0.8 μm CMOS technology. The detectors are monolithically integrated with the pixel electronics. The pixel pitch is 300×300 μm2. The measured gain is 1270 mV/fC at. 200-ns shaping time, and the ENC is 18 e- at 40-fF total input capacitance. The power dissipation per pixel is 2 mW at. 3.3 V.