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The response of PbWO4 to high-energy protons has been investigated in two test experiments at the proton beam facilities COSY and AGOR. The determined energy resolution below 360 MeV of σ/E = 0.97%/Eγ12/ + 3.33% is comparable to the previously deduced photon response. Energy spectra of inelastically scattered protons below 85 MeV are compared to similar distributions obtained for BaF2- and CeF3- detectors, respectively. The comparison to the response of charged pions indicates a strong quenching effect of the scintillation light for hydrogen isotopes.