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Time-domain reconstruction for thermoacoustic tomography in a spherical geometry

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2 Author(s)
Minghua Xu ; Opt. Imaging Lab., Texas A&M Univ., College Station, TX, USA ; Wang, L.V.

Reconstruction-based microwave-induced thermoacoustic tomography in a spherical configuration is presented. Thermoacoustic waves from biological tissue samples excited by microwave pulses are measured by a wide-band unfocused ultrasonic transducer, which is set on a spherical surface enclosing the sample. Sufficient data are acquired from different directions to reconstruct the microwave absorption distribution. An exact reconstruction solution is derived and approximated to a modified backprojection algorithm. Experiments demonstrate that the reconstructed images agree well with the original samples. The spatial resolution of the system reaches 0.5 mm.

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Medical Imaging, IEEE Transactions on  (Volume:21 ,  Issue: 7 )